Cigarette Smoke-Induced Emphysema and Pulmonary Hypertension Can Be Prevented by Phosphodiesterase 4 and 5 Inhibition in Mice.

PLoS One · 2015 · PMC4461257 · PMID 26058042

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showed a trendno p-value reported

Tadalafil treatment showed a trend toward reduction, and interestingly, no such effect was evident for the combination therapy ( Fig 7 ).

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