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Pre-referral rectal artesunate for severe malaria.

Cochrane Database Syst Rev · 2014 · PMC4463986 · PMID 24869943

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We also considered downgrading for imprecision because the result in Africa did not reach statistical significance without the addition of the Asian data.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.