Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.

Nat Commun · 2015 · PMC4469997 · PMID 26077951

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nominally significantno p-value reported

In an independent cohort of 67 autopsy-proven CBD cases from the Mayo Clinic Florida Brain Bank and 457 control individuals, a replication stage was performed for a total of seven SNPs: the top five SNPs from the discovery stage ( P <10 −5 ) and two PSP GWAS SNPs that showed nominally significant association with CBD (rs1768208 and rs242557) ( Table 2 ).

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a statistical trendno p-value reported

This identified a statistical trend for greater lnc-KIF13B-1 expression with the minor risk allele ( Supplementary Fig. 6 ).

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