EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.

This again showed no significant change in EphA7 expression in support of the flow cytometric data; there was an increase in EphA5 expression in EphA2 knockout MLL-A9 when compared to wild type MLL-AF9 leukemic cells, although this was variable and did not reach statistical significance ( Fig 6B ).

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