Ryanodine Receptor Activation Induces Long-Term Plasticity of Spine Calcium Dynamics.

PLoS Biol · 2015 · PMC4476683 · PMID 26098891

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a small trendno p-value reported

bAP-Ca 2+ Transient Plasticity in MEC Layer 2 and Hippocampal CA1 Spines We observed a small trend towards bAP-Ca 2+ transient run-up at the end of our control timelines, which is, however, not significantly different from a theoretical mean of 0% change when using a one sample t test ( Fig 1C 1 ).

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did not reach statistical significanceno p-value reported

The full effect size of CPA on enhancement could be matched with the specific RyR antagonist ryanodine and the reduction of enhancement observed with Xestospongin C (which has been demonstrated to affect VGCCs in mammalian preparations [ 28 ]) did not reach statistical significance when compared to controls.

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