In contrast, p65 Δ/Δ mice have only modest splenomegaly and modest elevation of neutrophil counts that did not reach statistical significance, compared to wild type mice ( Table 2 ).
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Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells.
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