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Preclinical Potency and Biodistribution Studies of an AAV 5 Vector Expressing Human Interferon-β (ART-I02) for Local Treatment of Patients with Rheumatoid Arthritis.

PLoS One · 2015 · PMC4479517 · PMID 26107769

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showed a trendno p-value reported
The effect on IL-6 production showed a trend towards a reduction.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.