Near-normoglycaemia and development of neuropathy: a 24-year prospective study from diagnosis of type 1 diabetes.

Dividing patients by low-cumulative and high-cumulative glycaemic exposure 3 after 27 years revealed a mean decrease in peroneal MNCV of 6.7 versus 13.0 m/s and sural SNCV of 8.1 versus 15.3 m/s, but the difference for these changes between the groups did not reach statistical significance. 23 CAN was assessed at the 18-year follow-up revealing abnormalities in ≥2 of 3 parameters in 29.4% of patients with mean HbA1c <8.4% compared with 66.7% in those with mean HbA1c ≥8.4%, but no prospective data was available. 24 Likewise, in the Stockholm Diabetes Intervention Study (SDIS), includi

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