Barely Significant
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The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication.

Nucleic Acids Res · 2015 · PMC4482075 · PMID 25855816

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Moreover, although the differences in titer among wt, Mutants A and B viruses did not reach statistical significance, the titer of Mutant A trended slightly higher than those of the other two variants.

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