Substitution in Amino Acid 70 of Hepatitis C Virus Core Protein Changes the Adipokine Profile via Toll-Like Receptor 2/4 Signaling.

PLoS One · 2015 · PMC4487891 · PMID 26121241

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did not reach statistical significanceno p-value reported

IL-6 induction of 3T3-L1 cells treated by HCV core protein was significantly inhibited with anti-TLR2 antibody by 42% in the 70Q group (p<0.05) and by 31% in the 70R group, though it did not reach statistical significance, probably due to the small number of samples ( Fig 6A ).

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