t-Darpp Promotes Enhanced EGFR Activation and New Drug Synergies in Her2-Positive Breast Cancer Cells.

In SRB cell proliferation assays, SK.tDp cells were 3- to 5-fold more sensitive than SK.empty cells to AG1478, gefitinib and erlotinib, whereas SK.dDp cells demonstrated an intermediate sensitivity that did not reach statistical significance ( Fig 3B ).

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