marginally significantP =0.059
Our analysis revealed a marginally significant lower number of duplication events in AD+P cases compared with AD−P controls ( P =0.059) using multivariable regression model.
Our analysis revealed a marginally significant lower number of duplication events in AD+P cases compared with AD−P controls ( P =0.059) using multivariable regression model.
34 The resulting nominally significant CNV regions were excluded if they met either of the following criteria: (i) residing on telomere- or centromere-proximal cytobands; (ii) located in a 'peninsula' of common CNVs arising from variation in boundary truncation of CNV calling.
It is worth noting that this result was highly significant even under the ordered model that we fit.