Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates.

Sci Rep · 2015 · PMC4490344 · PMID 26139288

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

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boldest claim

The sentences

did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

CD8 + depletion reduced sterile protection from 4/7 (57.1%) in the IgG control group to 1/8 (12.5%), but did not reach statistical significance (p = 0.07). 2/8 (25%) mice were sterilely protected after CD4 + depletion, a statistically greater level than compared to the naïve control group (p = 0.0003), suggesting these mice are still afforded with some protection.

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