Neuronal c-Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N-terminus are moderate.

However, opposite effects were observed on cell size ( Figure S1 m): in jun F/F controls, average neuronal cell diameter showed a trend towards increase on the axotomized side, from 21.5 ± 0.7 um for the uninjured to 23.2 ± 0.8 um for injured motoneurons ( p = 0.085), the jun ΔS mice a decrease from 22.1 ± 0.3 to 15.5 ± 0.8 um ( p < 0.005).

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