Use of Contrast-Enhanced Ultrasound in Carotid Atherosclerotic Disease: Limits and Perspectives.

Biomed Res Int · 2015 · PMC4491377 · PMID 26180793

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did not reach statistical significanceno p-value reported

Ten studies (41%, 578 patients) evaluated the correlation between CEUS images and the presence of ipsilateral neurological symptoms: in three cases (30%, 91 patients) results did not reach statistical significance to demonstrate that plaques with greater contrast enhancement are more frequently related to clinical symptoms.

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highly significantno p-value reported

The correlation between data obtained with CEUS and histopathologic results was performed in 12 studies (50%, 433 patients) and all the studies found a statistical significant correlation: plaques with higher enhancement have a highly significant vascularization of the plaque.

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