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Optimization of HIV-1 Envelope DNA Vaccine Candidates within Three Different Animal Models, Guinea Pigs, Rabbits and Cynomolgus Macaques.

Vaccines (Basel) · 2013 · PMC4494233 · PMID 26344115

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The same constructs were also used to immunize rhesus macaques [ 34 ] and although syn.gp150 Bx08 antisera showed slightly higher in vitro neutralizing activity than syn.gp140 Bx08 antisera of homologous HIV-1 Bx08 , the difference did not reach statistical significance.

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