Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance.

The analysis demonstrated a significant association between loss of nNCoR localization and higher mitotic index ( p < 0.01) and a statistical trend with ulceration ( p = 0.051) (see Table 1 ).

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In our MM series, we found that the presence of nuclear p65-NF-κB in MM cells was associated with advanced disease, although the correlation between nuclear p65-NF-κB and cytoplasmic accumulation of NCoR did not reach statistical significance in these tumors.

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