Complementary action of granulocyte macrophage colony-stimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: rationale for combination therapy in rheumatoid arthritis.

Arthritis Res Ther · 2015 · PMC4496892 · PMID 26081345

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did not reach statistical significanceno p-value reported

A reduction in total CII-specific IgG was seen in the mice receiving anti-GM-CSF treatment, but it did not reach statistical significance (Fig. 2e ).

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