Rapid and Progressive Regional Brain Atrophy in CLN6 Batten Disease Affected Sheep Measured with Longitudinal Magnetic Resonance Imaging.

PLoS One · 2015 · PMC4498759 · PMID 26161747

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showed a trendno p-value reported

As well as progressive atrophy, we noted that atrophy first became measurable in the thalamus during the period of study and hippocampal volume showed a trend towards a significant volume change, although this did not survive correction for multiple comparisons.

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