Incubation of vessels with propionaldehyde under normoxic conditions blunted the vasorelaxant effect of low concentrations of nitrite without affecting its efficacy at higher concentrations, but these differences did not reach statistical significance ( P > 0.05; by two-way anova ; Figure 2 C).
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Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans.
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