Potential effect on the aortic valve The ramipril group showed a trend towards reduced progression of the AS (change in valve area 0 vs. −0.2 cm 2 in the ramipril and placebo groups respectively, though the statistical strength of the difference was weak ( P = 0.067).
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A prospective, double-blind, randomized controlled trial of the angiotensin-converting enzyme inhibitor Ramipril In Aortic Stenosis (RIAS trial).
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