showed a trendp< 0.001
However, when compared with healthy controls, we found that the patients with CFEOM1 showed a trend of ALFF increase (p< 0.001, uncorrected) in the right inferior parietal lobe and right frontal cortex and also a trend of ReHo increase (p<0.001 uncorrected) in the left precentral gyrus, left orbital frontal cortex, temporal pole and the posterior division of cingulate gyrus ( Table 3 and Fig 3 ).