Identification of sequences common to more than one therapeutic target to treat complex diseases: simulating the high variance in sequence interactivity evolved to modulate robust phenotypes.

3’UTR is also the main target of miRNAs and, interestingly, the distribution of the nucleotide sequences described in this study as having therapeutic potential for multitargeting also show a significant trend toward being more commonly located in the 3’UTR, with decreasing frequency approaching the 5’UTR (Fig. 3c ).

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