Circulating microRNA-144-5p is associated with depressive disorders.

The relationships between miR-144-5p and two depression scores at baseline, HADS-D (β=-0.02, p=0.02) and PHQ-9 (β=-0.02, p=0.06) were also significant or borderline significant, whereas the association with HADS-A score (β=-0.01, p=0.37) was non-significant (Table S2c) .

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The finding of an inverse correlation between plasma miR-144-5p levels and the MADRS-S at baseline was also present for the other two depression scores, i.e., Hospital Anxiety and Depression Scale (HADS)-D and PHQ-9; however, the results for HADS-D and PHQ-9 did not reach statistical significance.

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