Among the 39 children with no RTV-sPI exposure there was a trend for risk of major PI mutation if they also received TB treatment; however, the numbers were small and did not reach statistical significance OR = 2.0 [95% CI 0.5 to 9.8].
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Factors Associated with the Development of Drug Resistance Mutations in HIV-1 Infected Children Failing Protease Inhibitor-Based Antiretroviral Therapy in South Africa.
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