CCR4 Controls the Suppressive Effects of Regulatory T Cells on Early and Late Events during Severe Sepsis.

Despite the fact that the differences in Tregs numbers in the peritoneal cavity between the groups did not reach statistical significance, it is important to highlight that there was a tendency of an increase in the Tregs number in the L-WT group compared with the sham-WT group, while such an increase was not observed in the L-CCR4 -/- group ( Fig 4A ).

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