Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity.

PLoS One · 2015 · PMC4514594 · PMID 26207899

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showed a trendP value = 0.10so close (0.05 < p ≤ 0.1)

This experiment revealed that tumor-bearing mice treated with TM5441 (20 mg/kg daily) showed a trend to develop slower growing tumors that reached a volume of 1,500 mm 3 at an average of 25.8 (± 3.4) days vs. 21.2 (± 2.5) days for the control group ( P value = 0.10) ( Fig 5A and 5B ).

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