Explore the dynamic alternation of gene PLAC4 mRNA expression levels in maternal plasma in second trimester for nonivasive detection of trisomy 21.

Obstet Gynecol Sci · 2015 · PMC4515474 · PMID 26217595

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did not reach statistical significanceno p-value reported

It has previously been reported that there was a trend toward an increased PLAC4 mRNA concentration in the maternal plasma of T21 pregnancies, but the increase did not reach statistical significance [ 9 ].

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