Although transaminase increases were common with trabectedin, they followed a predictable pattern with a peak elevation at days 5–7 and a return to grade ≤1 at approximately day 15 of each cycle, and with a clear trend towards reduction with subsequent cycles ( Fig. 4 ) 10 , 17 .
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Lack of Correlation Between Liver Tests Abnormalities and Trabectedin Efficacy in the Treatment of Soft Tissue Sarcoma: a Retrospective Study.
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