An increasing trend of ACOXL protein expression loss in more poorly differentiated and aggressive tumors was also noted.
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Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer.
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Separating the tumor category into Gleason grades and metastatic tumors showed a trend for decreased ACOXL expression in more advanced and aggressive tumors.