Role of Central Serotonin in Anticipation of Rewarding and Punishing Outcomes: Effects of Selective Amygdala or Orbitofrontal 5-HT Depletion.

Cereb Cortex · 2015 · PMC4537445 · PMID 24879752

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hedged sentences

0.0030

closest p · 0.1× alpha

0.0860

boldest claim

The sentences

highly significantP = 0.003actually significant

For false feedback, there was a highly significant effect of Lesion ( F 2,9 = 12.4, P = 0.003); pairwise comparisons between groups demonstrated that the amygdala-depleted groups were more likely to obey misleading feedback than controls ( F 1,6 = 26.1, P = 0.002) or OFC-depleted animals ( F 1,6 = 8.32, P = 0.028), while the OFC and control groups

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near-significantP = 0.086so close (0.05 < p ≤ 0.1)

In contrast, the 5-HT OFC-depleted animals showed significant ( P = 0.014) and 5-HT-amygdala-depleted animals near-significant ( P = 0.086) increases in the total number of responses made after punishment introduction.

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