Response to Infliximab in Crohn's Disease: Genetic Analysis Supporting Expression Profile.

Mediators Inflamm · 2015 · PMC4539178 · PMID 26339133

Europe PMC DOI

hedged sentences

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

showed a trendP = 0.1so close (0.05 < p ≤ 0.1)

In contrast, in the TNFAIP6 gene, the most frequent CAGA haplotype only showed a trend for association in ileal patients ( Table 4(c) , CAGA haplotype: P = 0.1; OR (95% CI) = 0.57 (0.27–1.17)), while no difference was detected in colonic patients ( Table 5(c) ). 4.

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borderline significanceno p-value reported

In this case, association with borderline significance has been found involving an IL11 haplotype with decreased frequency in CD responders to IFX.

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