highly significantp = 0.009
For the chorea subscore the difference between baseline and 6 months was highly significant: 13.5 compared to 5.2 points (−8 (60.6%), p = 0.009).
For the chorea subscore the difference between baseline and 6 months was highly significant: 13.5 compared to 5.2 points (−8 (60.6%), p = 0.009).
Concerning secondary endpoints in the non-Westphal subgroup the BFMDRS disability score improved significantly and the HD-ADL and SF-36 mental health score showed a trend toward improvement.
In accordance with the exclusion criteria, patients showed normal mood and psychiatric scores at baseline, however HADS-D (depression) improved significantly ( p = 0.044), and MADRS and BPRS showed a statistical trend toward improvement.