A placebo-controlled trial of dextromethorphan as an adjunct in opioid-dependent patients undergoing methadone maintenance treatment.

Int J Neuropsychopharmacol · 2015 · PMC4540107 · PMID 25716777

Europe PMC DOI

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0.0100

closest p · 0.2× alpha

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boldest claim

The sentences

a significant trendp = 0.010actually significant

The plasma morphine level in the DM120 group did not change significantly (F = 0.780, p = 0.539), but the placebo group showed a significant trend of increasing plasma morphine levels (F = 3.387, p = 0.010), and the DM60 group showed a significant trend of decreasing plasma morphine levels (F = 3.051, p = 0.018).

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