A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy.

Cell Death Dis · 2014 · PMC4540206 · PMID 25255218

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slightly significantno p-value reported

A slightly significant increase of Cer after TMZ treatment was observed at 48 h.

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