A phylo-functional core of gut microbiota in healthy young Chinese cohorts across lifestyles, geography and ethnicities.

Using the first 198 principal coordinates (accounting for 82.85% of the total variation), 223 individuals were successfully predicted by their ethnicities, yielding a cross-validated correct classification rate (CCR) of 71.02% as well as the highly significant canonical test statistics ( P =0.0001).

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Additionally, other potential factors, such as sex, showed a trend but not significant in the segregation of the gut microbiota structure across all the individuals ( P =0.0531).

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Similarly, PERMANOVA revealed that the impact of lifestyle was most significant within the Mongol and Zhuang ethnic groups, followed by the Han cohorts living in Harbin and Zhengzhou, whereas this impact was marginally significant in the Tibetan cohorts (see Table 1 for the corresponding P -values).

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