Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects.

J Biol Chem · 2015 · PMC4543653 · PMID 26139601

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did not reach statistical significanceno p-value reported

Quantitative PCR revealed a trend for a reduction in mitochondrial DNA (ratio of cytochrome b DNA to Aprt DNA) that did not reach statistical significance, possibly due to the presence of non-β cells as well as non-recombined β cells in the islet preparations.

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