Rare coding mutations identified by sequencing of Alzheimer disease genome-wide association studies loci.

Ann Neurol · 2015 · PMC4546546 · PMID 26101835

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highly significantno p-value reported

A stop‐gain mutation in ABCA7 (E1679X) and missense mutation in CD2AP (K633R) were highly significant in Caucasian LOAD cases, and mutations in EPHA1 (P460L) and BIN1 (K358R) were significant in Caribbean Hispanic families with LOAD.

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nominally significantno p-value reported

The EPHA1 variant segregated completely in an extended Caribbean Hispanic family and was also nominally significant in the Caucasians.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.