Exposure of Monocytes to Lipoarabinomannan Promotes Their Differentiation into Functionally and Phenotypically Immature Macrophages.

Total CD68 expression on unexposed mature macrophages was significantly higher than that observed on fresh monocytes, a result that is consistent with previous reports [ 15 ]; however, it appears that when monocytes were exposed to LAM for 48-to-72 h, the cells tended to reduce CD68 expression ( Figure 3(b) ), though this result did not reach statistical significance.

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