A Novel Prime and Boost Regimen of HIV Virus-Like Particles with TLR4 Adjuvant MPLA Induces Th1 Oriented Immune Responses against HIV.

PLoS One · 2015 · PMC4552547 · PMID 26312747

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did not reach statistical significanceno p-value reported

Although both CALV(7.5)+VLP (23.3%) and CALV(12.5)+VLP (27.0%) groups had higher mean percentages of germinal center B cells, these trends did not reach statistical significance when compared with control values.

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