Induced pluripotent stem cell models of Zellweger spectrum disorder show impaired peroxisome assembly and cell type-specific lipid abnormalities.

Relative sVLCFA levels were significantly reduced in patient compared to control iPSCs cultured in iPSC growth media (5.0-fold, P = 0.001); however, differences in %C26:0LPC did not reach statistical significance (Table 2 , Additional file 3 ).

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