Barely Significant
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Colchicine in cardiac disease: a systematic review and meta-analysis of randomized controlled trials.

BMC Cardiovasc Disord · 2015 · PMC4553011 · PMID 26318871

Europe PMCDOI
1
hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)
In 5 trials, n = 1301) at risk for cardiovascular disease (coronary artery disease, acute coronary syndrome or stroke, post-angioplasty [2 RCTs], or congestive heart failure), colchicine reduced composite cardiovascular outcomes by ~60 % (risk ratio [RR] 0.44, 95 % confidence interval [CI] 0.28-0.69, p = 0.0004; I 2 = 0 %) and showed a trend towards lower all-cause mortality (RR 0.50, 95 % CI 0.23-1.08, p = 0.08; I 2 = 0 %).

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