Comparative Analysis of Cesium Chloride- and Iodixanol-Based Purification of Recombinant Adeno-Associated Viral Vectors for Preclinical Applications.

Hum Gene Ther Methods · 2015 · PMC4554548 · PMID 26222983

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a clear trendno p-value reported

Whereas the AAV capsid proteins VP1 (87 kDa), VP2 (73 kDa), and VP3 (62 kDa) were visible mainly in fractions 15–20, relatively strong background and several distinct protein contaminants were visible in all fractions, with a clear trend toward more contamination in the upper fractions, particularly fractions 20 and 21 ( Fig. 2c ).

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