Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease.

PLoS One · 2015 · PMC4556375 · PMID 26322888

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0700

boldest claim

The sentences

approached significancep< 0.06so close (0.05 < p ≤ 0.1)

Circulating ADMA increased and approached significance (p< 0.06).

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almost reached statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

While the levels of arginine were unchanged, MMA and ADMA were significantly reduced (p< 0.01 and p< 0.05, respectively) and SDMA reduction almost reached statistical significance (p = 0.07) with HFHC diet ( Fig 3E ).

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