Mesenchymal Stromal Cell-Derived Factors Promote Tissue Repair in a Small-for-Size Ischemic Liver Model but Do Not Protect against Early Effects of Ischemia and Reperfusion Injury.

In contrast, 48 hours after IRI + PH serum ALT and AST levels were markedly lower in the MSC-CM treated animals compared to the UM treated animals, though differences did not reach statistical significance (MSC-CM versus UM treatment: ALT 138 ± 35 IU/L versus 764 ± 399 IU/L, p = 0.18, and AST 248 ± 41 IU/L versus 1008 ± 484 IU/L, p = 0.14; Figures 3(c) and 3(f) ). 3.3.

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