Pathogenicity of Anti-ADAMTS13 Autoantibodies in Acquired Thrombotic Thrombocytopenic Purpura.

Patients with both anti-N- and C-terminal antibodies with inhibitory function showed a trend to lower ADAMTS13 antigen levels, compared to those with anti-N-terminal alone [median 30 ng/ml (3.2%); range 0–356 ng/ml; p = 0.08] ( Fig. 5 B).

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