Comet assay measures of DNA damage as biomarkers of irinotecan response in colorectal cancer in vitro and in vivo.

Cancer Med · 2015 · PMC4567016 · PMID 26108357

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did not reach statistical significanceno p-value reported

In 32 assessable patients, it was observed that SN-38 induced DNA damage following 1 h treatment was generally lower in those with PD but this did not reach statistical significance (Fig. 5 A).

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