A Randomized, Double-Blind, Placebo-Controlled Trial of Adjunctive Metformin Therapy in Overweight/Obese Youth with Type 1 Diabetes.

PLoS One · 2015 · PMC4569440 · PMID 26367281

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nearly significantno p-value reported

This is particularly important in interpreting the results that were nearly significant such as the change in the TDD of long-acting insulin in which the metformin group had a consistently lower requirement for long-acting insulin throughout the trial compared to the placebo group (p = 0.221).

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