Association of KCNB1 polymorphisms with lipid metabolisms and insulin resistance: a case-control design of population-based cross-sectional study in Chinese Han population.

In addition, genotype AT was associated with increased TC levels ( P = 0.049, b = 0.16(0.00, 0.32)), insulin resistance ( P = 0.03, b = 0.74(0.06, 1.42)), and fasting insulin (FINS) ( P = 0.02, b = 0.10 (0.01, 0.19)) compared with genotype TT, and showed a trend in increasing islet β-cell function by HOMA-B% ( P = 0.09, b = 5.66(-0.86, 12.18)) (Table 1 ). rs1051295: Compared with genotype CC, both of genotype TT ( P = 0.03, b = 0.06 (0.01, 0.12)) and TC ( P = 0.10, b = 0.10(-002, 0.22)) was associated or inclined to be associated with increased serum TG levels, in line with our previous report [ 2 ].

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