Although descriptive analysis suggested that activity levels were lower in the MPS III group compared to controls for the second time quadrant (6 am–12 pm), this difference did not reach statistical significance ( U = 18.0, z = −1.47, p = 0.141, r = 0.38 (medium-large effect)).
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Actigraphic investigation of circadian rhythm functioning and activity levels in children with mucopolysaccharidosis type III (Sanfilippo syndrome).
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The sentences
There was a marginal trend towards lower relative amplitude in the MPS III group, suggesting that there was less differentiation between the most and least active phases over the 24-h period compared to TD controls.